Content

Strategic insights on blockchain, AI, security, leadership, and career in an age of disruption.

Quantum Computing's Hidden Opportunity in Drug Discovery
June 05, 2026·5 min read
AI
Opinion

Quantum Computing's Hidden Opportunity in Drug Discovery

Quantum computing can accelerate drug discovery by simulating molecular interactions classical computers can't model. Learn why pharma leaders should balance security risks with transformative R&D potential.

Recent Essays

#ai strategy

34 posts

The Thinking Gap: Why AI Speed Kills Originality
June 04, 2026Opinion

The Thinking Gap: Why AI Speed Kills Originality

AI gives answers instantly, but skips the thinking process where real innovation happens. Guard your unstructured thinking time before reaching for the prompt.

AI Cost Risk: Why Treasury Owns AI Now
June 03, 2026

AI Cost Risk: Why Treasury Owns AI Now

Wall Street's new AI futures markets transform compute from IT expense to financial risk. Learn who should own AI cost hedging at your firm.

Quantum Computing Beyond Security: Solving Unsolved Problems
May 29, 2026Opinion

Quantum Computing Beyond Security: Solving Unsolved Problems

Discover how quantum computers could revolutionize nitrogen fixation and industrial processes, moving beyond cybersecurity threats to unlock scientific breakthroughs worth billions.

AI Jobs Debate: Research Shows What Actually Matters
May 28, 2026Opinion

AI Jobs Debate: Research Shows What Actually Matters

New University of Vaasa study reveals AI's real career impact: collaborative adoption wins, while resistance loses. The threat isn't AI—it's professionals who ignore it.

Quantum Computing: Building New Systems, Not Faster Horses
May 22, 2026Opinion

Quantum Computing: Building New Systems, Not Faster Horses

Quantum computing isn't just faster—it enables entirely new categories of computation and business models previously impossible. Organizations that build new capabilities will outpace those defending against threats.

The Real Fingerprint of AI-Driven Layoffs
May 18, 2026

The Real Fingerprint of AI-Driven Layoffs

Cloudflare's restructuring reveals what genuine AI labor displacement looks like: growing revenue, cuts below prior headcount, spared customer teams, and 600% internal AI usage growth.

Org Design Shift: AI and the 5-Layer Control Framework
May 12, 2026Opinion

Org Design Shift: AI and the 5-Layer Control Framework

AI enables flatter organizations with 5 layers instead of 8-12. Finance leaders must redesign controls around autonomous pods and AI-assisted decisions.

The Real Math Behind AI-Native Layoffs
May 11, 2026

The Real Math Behind AI-Native Layoffs

CEOs blame AI for restructuring, but the numbers tell a different story. Learn the diagnostic questions that reveal whether layoffs are genuine transformation or corrective hiring decisions.

AI Cost Reality: When Subsidies End
May 01, 2026

AI Cost Reality: When Subsidies End

Compute subsidies are temporary. Learn how to build sustainable AI products that survive price increases and compete beyond today's token economics.

AI Is Reshaping Legal Pricing—Your Industry Is Next
April 27, 2026Opinion

AI Is Reshaping Legal Pricing—Your Industry Is Next

Big law firms are cutting associate classes and shifting to fixed fees as AI transforms service delivery. Here's why this signals disruption across professional services.

AI Governance: Balance Adoption and Risk
April 23, 2026Opinion

AI Governance: Balance Adoption and Risk

Leaders face competing pressures on AI: boards demand adoption, risk committees demand controls. Learn how to govern AI as a critical dependency, not a strategic choice.

Navigating AI Risk: The Third Path Beyond Speed vs. Caution
April 08, 2026Opinion

Navigating AI Risk: The Third Path Beyond Speed vs. Caution

Across three tech disruption cycles, organizations that balanced aggressive innovation with responsible guardrails outperformed both speed-first and caution-first competitors. Here's what that means for AI.

Jay Schulman — Plan for Thursday